Retreat to our well-appointed Houston Medical Center hotel

Marriott Rewards Category 7 · Points needed per night

Discover why the Houston Marriott Medical Center/Museum District is a preferred choice among hotels near the Texas Medical Center. Situated steps from leading hospitals, research centers and clinical facilities, including M.D. Anderson Cancer Center, our hotel ensures travelers enjoy a restful, relaxing stay. It begins with our refreshed, modern accommodations, all of which feature the latest in technology. After a restful night's sleep, stop by Driscoll's, our signature restaurant, for a hearty breakfast buffet before exploring the local area. Situated in downtown Houston, we're ideally located near the Museum District, Rice University and NRG Stadium. A premier destination for events, meetings and weddings, our hotel also features over 8,700 square feet of sophisticated venue space in Houston's city center. Whether you are traveling to the area for an extended-stay business trip or taking a weekend getaway, the Houston Marriott Medical Center/Museum District looks forward to welcoming you.

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Guest reviews

Confirmed guest reviews
4.4 out of 5.0
92% of guests recommend this hotel

Hear from our guests about their stay from 687 confirmed guest reviews

Key amenities

  • Fitness center
  • Pool
  • Kitchen/kitchenette
  • Meeting event space


  • Visit local attractions like the Houston Museum District, Rice University, the Houston Zoo and NRG Stadium from our hotel.

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  • Take advantage of superb hotel amenities like two restaurants, a full fitness center and an indoor pool in the heart of downtown Houston, Texas.

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  • Benefit from our superb location near the Texas Medical Center's array of leading hospitals and clinics, including the M.D. Anderson Cancer Center.

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Guest rooms

Stretch out in our stylish downtown Houston hotel

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Houston Marriott® Medical Center/Museum District