New Hotel

A New Level of Well-Being, Cleanliness, and Service!

Rewards Category 4 Points needed per night

Among Jacksonville, FL hotels, the brand new Residence Inn Jacksonville - Mayo Clinic Area is uniquely positioned and customer focused, providing a clean and comfortable environment featuring an array of amenities and special care services. Located just 3 minutes to Mayo Clinic, a complimentary shuttle is provided. When you want to explore Jacksonville, we're (3 mi) to the Atlantic Ocean, (5 mi) to University of North Florida and only (17 mi) to all of the excitement in Downtown Jacksonville. All of our suites feature a fully equipped kitchen, living area, free WiFi, sofabed, 55" SMART HDTV with Netflix. When looking to relax, take a dip in our outdoor swimming pool or enjoy a beverage and a bite to eat at our lobby bar. Enjoy the benefit of a great workout in our state-of-the art fitness center. Book your next event with us featuring 4,128 sq ft of flexible meeting and outdoor space for up to 120 people. We look forward to serving you and to extending our warm hospitality.

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Guest reviews

4.4 out of 5.0

Hear from our guests about their stay from 64 confirmed guest reviews

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Key amenities

  • Kitchen
  • Free high-speed internet
  • Free breakfast
  • Pet friendly


  • Within 1 mile to Mayo Clinic. This all-suite hotel offers free shuttle to Mayo

  • We're experts in Extended Stay hotel visits, our goal is to make you feel at home

  • Meeting and banquet accommodations to accommodate up to 120 people

Guest rooms

Relaxing Suites with full kitchens near Mayo Clinic

  • King Studio Suite - Sleeping Area

    King Studio Suite

    Studio, 1 King, Sofa bed
  • One-Bedroom Queen/Queen Suite

    One Bedroom Suite 2 Queen

    1 Bedroom 2 room Suite, 2 Queen, Sofa bed
  • King Studio Suite - Sleeping Area

    King Corner Studio Suite

    Larger Studio, 1 King, Sofa bed, Corner room

Check room rates & availability

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