Discover the newly renovated Residence Inn Rochester Mayo Clinic Area, the ideal choice for downtown Rochester, MN hotels. It combines the familiar comforts of home with passionate guest service whether your stay is for one night or thirty. Relax in your choice of 89 spacious with studio, one, and two-bedroom options. Only 9 miles from the Rochester International Airport (RST) and providing direct access to the world-famous Mayo Clinic via the climate-controlled pedestrian subway and skyway, the Residence Inn Rochester Mayo Clinic Area is in a perfect downtown location. In addition, our hotel in downtown Rochester, MN is also centrally located to St. Mary’s Hospital and Rochester Methodist Hospital and is designed as an extended stay hotel. Nearby attractions include Mayowood Mansion, Assisi Heights, and Silver Lake Park. For nearby shopping visit The Grand Shops or Apache Mall. Graham Arena & the Olmsted County Fairgrounds are 2 miles away. We look forward to your stay at our Residence Inn.