Head South on Col Eileen Collins Blvd, use the right lane to take Interstate 81 S ramp to Interstate 90 Thruway/Syracuse. Use the left lane to continue toward I-81 S. Keep left, follow signs for Interstate 81 S/Interstate 90/Syracuse and merge onto I-81S. Continue on for 6.0 miles. Take Exit 18 toward Harrison St/ Adams St. Merge onto Harrison St Turn Right onto South Warren St. Hotel will be on the left.