Follow signs from the airport to the Centrum for approximately 10km. You will pass the football stadium on the left and large park open area on the right. At the next crossroad turn right to the tunnel. After the tunnel continue straight across the bridge. At the traffic lights turn left, keep in the right line while turning left and than right on traffic lights. Continue straight until the next tunnel. After the tunnel at the traffic lights turn right and drive past the big hotel on your left, through two sets of traffic lights, then turn right at the next set of lights. At the next junction turn left, and follow the road right to the next road junction. Turn left and continue straight through the set of traffic light and than follow the road until you rich next intersection. Turn left and the Boscolo Prague hotel is situated across the street on your left hand side.